441. Mindy Levine, Daniel
Mazori and Ronald Breslow, “Enantioselective Synthesis and Enantiomeric Amplification
of Amino Acids under Prebiotic Conditions.” Org.
Lett., 2008, 10,
2433-2436.
2007 Top
440.
Jordan R. Quinn, Frank W. Foss, Jr., Latha Venkataraman, and Ronald Breslow,
“Oxidation Potentials Correlate with Conductivities of Aromatic Molecular
Wires,” J. Am. Chem. Soc., 2007, 129, 12376-12377.
439.
Ronald Breslow, “A Fifty-Year Perspective on Chemistry in Water,” in Organic Reactions in Water, Marcus
Lindstrom, ed., Blackwell Publishers, Oxford, 2007, pp. 1-28.
438.
Jordan R. Quinn, Frank W. Foss, Jr., Latha Venkataraman, Mark S. Hybersten and
Ronald Breslow, “Single-Molecule Junction Conductance through Diaminoacenes,” J. Am. Chem. Soc., 2007, 129, 6714-6715.
437. Ronald Breslow, Sujun Wei, and Craig Kenesky,
“Enantioselective Transaminations by Dendrimeric Enzyme Mimics,” Tetrahedron, 2007, 63, 6317-6321.
436. Subhajit Bandyopadhyay, Wenjun Zhou and
Ronald Breslow, “Isotactic Polyethylenimines Induce Formation of L-Amino Acids
in Transamination,”Org. Lett. 2007, 9, 1009-1012.
435.
Paul A. Marks and Ronald Breslow, “Dimethylsulphoxide to vorinostat:
development of this histone deacetylase inhibitor as an anticancer drug,” Nature Biotech. 2007, 25, 84-90.
434. Ronald Breslow, “The
Hydrophobic Effect in Reaction Mechanism Studies and in Catalysis by Artificial
Enzymes,” J. Phys. Org. Chem. 2006,
19, 813-822.
433. Ronald Breslow,
Subhajit Bandyopadhyay, Mindy Levine, and Wenjun Zhou, “Water Exclusion and
Enantioselectivity in Catalysis,” ChemBioChem
2006, 7, 1491-1496.
432. Ronald Breslow and Mindy Levine, “Amplification of
enantiomeric concentrations under credible prebiotic conditions,” Proc. Nat. Acad. Sci. USA 2006, 103, 12979-12980.
431. Ronald Breslow and Mindy Levine, "Partial transfer of
enantioselective chiralities from alpha-methylated amino acids, known to be of
meteoritic origin, into normal amino acids," Tetrahedron Lett.
2006, 47,
1809-1812.
430. Zhenglai Fang and Ronald Breslow, "Metal
Coordination-Directed Hydroxylation of Steroids with a Novel Artificial P-450
Catalyst," Org. Lett. 2006, 8, 251-254.
429.
Iris W. Tam, Jiaming Yan, and Ronald Breslow; "An 11nm Molecular Wire that
Switches Elechrochemically between and Insulating and a Fully Conjugated
Conducting State," Org. Lett. 2006, 8, 183-185.
428.
Xuefeng Guo, Joshua P. Small, Jennifer E. Klare, Yiliang Wang, Meninder S.
Purewal, Iris W. Tam, Byung Hee Hong, Robert Caldwell, Limin Huang, Stephen
O'Brien, Jiaming Yan, Ronald Breslow, Shalom J. Wind, James, Philip Kim, Colin
Nuckolls, "Covalently Bridging Gaps in Single-Walled Carbon Nanotubes with
Conducting Molecules," Science
2006, 311, 356-359.
2005 Top
427. Christopher Uyeda, Mark Biscoe,
Paul LePlae and Ronald Breslow, "Hydrophobically directed selective reduction
of ketones using amine boranes," Tetrahedron
Lett.
2005, 47, 127-130.
426.
Zhenglai Fang and Ronald Breslow, "A Thiolate Ligand on a Cytochrome P-450
Mimic Permits the Use of Simple Environmentally Benign Oxidants for Biomimetic
Steroid Hydroxylation in Water," Biorg.
Med. Chem. Lett. 2005, 15, 5463-5466.
425. Jason J. Chruma, Lei Liu, Wenjun Zhou and Ronald Breslow,
"Hydrophobic and electronic factors in the design of dialkylglycine
decarboxylase mimics," Bioorg. Med.
Chem. 13, 5873-5883 (2005).
424.
Mark R. Biscoe and Ronald Breslow, "Oxaziridinium Salts as Hydrophobic
Epoxidation Reagents: Remarkable Hydrophobically-Directed Selectivity in Olefin
Epoxidation," J. Am
.Chem. Soc. 127, 10812-10813 (2005).
423.
Lei Liu and Ronald Breslow, "Vitamin B6 Enzyme Models, in "Artificial
Enzymes," R. Breslow, ed., Wiley-VCH, Weinheim, Germany, 2005, pp. 37-62.
422.
R. Breslow, "Artificial Enzymes," in "Artificial Enzymes,"
R. Breslow, ed., Wiley-VCH, Weinheim, Germany, 2005, pp. 1-35.
421.
R. Breslow, ed., "Artificial Enzymes," Wiley-VCH, Weinheim, Germany,
2005.
420.
W. Zhou, N. Yerkes, J. J. Chruma, L. Liu, and R. Breslow, "Chiral
polyamines from reduction of polypeptides: asymmetric pyridoxamine-mediated
transaminations", Bioorg. Med. Chem.
Lett. 15. 1351-1355 (2005).
2004 Top
419.
M. R. Biscoe, C. Uyeda, and R. Breslow, "Requirements for Selective
Hydrophobic Acceleration in the Reduction of Ketones", Org. Lett. 6,
4331-4334 (2004).
418.
D. Bong, I. Tam, and R. Breslow, "Oligothiophene Isocyanides for
Platinum-Based Molecular Electronic Applications", J. Amer. Chem. Soc. 126, 11796-11797 (2004).
417. R. Breslow, "Determining the Geometries of Transition
States by Use of Antihydrophobic Additives in Water," Accts. Chem. Res. 37,
471-478 (2004).
416.
L. Liu and R. Breslow, "Polymeric and dendrimeric pyridoxal enzyme
mimics," Bioorg. Med. Chem. 12,
3277-3287 (2004).
415. L. Liu, W. Zhou, J. Chruma, and R. Breslow,
"Transamination Reactions with Multiple Turnovers Catalyzed by Hydrophobic
Pyridoxamine Cofactors in the Presence of Polyethylenimine Polymers," J. Am. Chem. Soc. 126, 8136-8137 (2004).
414.
T. Ito, Y. Fudamoto, A. Fukaya, I. M. Gat-Malureanu, M. I. Larkin, P. L. Russo,
A. Savici, Y. J. Uemura, K. Groves, R. Breslow, K. Hotehama, S. Yamanaka, P.
Kyriakou, M. Rovers, G. M. Luke, K. M. Kojima, "Two-dimensional nature of
superconductivity in the intercalated layered systems LixHfNCl and LixZrNCl:
Muon spin relaxation and magnetization measurements," Phys. Rev. B 69, 134522/1-134522/13 (2004).
2003 Top
413.
R. Breslow, "Polymeric enzyme mimics," Polymer Preprints 44, 480
(2003).
412.
R. Pearman, D. T. Bong, R. Breslow, and G. W. Flynn, "Nanostructured
thiophenes through self-assembly: Toward molecular electronics," Poly.
Mat. Sci. and Engin. 89, 213 (2003).
411.
M. R. Biscoe and R. Breslow, "Hydrophobically Directed Selective Reduction
of Ketones," J. Am. Chem. Soc. 125, 12718-12719 (2003).
410.
M. Leivers, I. Tam, K. Groves, D. Leung, Y. Xie, and R. Breslow, "A
Forbidden Rearrangement," Org. Lett. 5, 3407-3409
(2003).
409.
L. Liu and R. Breslow, "Dendrimeric Pyridoxamine Enzyme Mimics," J.
Am. Chem. Soc. 125, 12110-12111 (2003).
408. W. Zhou, L. Liu, and R. Breslow, "Transamination by
Polymeric Enzyme Mimics," Helv.
Chim. Acta 86, 3560-3567 (2003).
407.
D. Wilson, L. Perlson, and R. Breslow, "Helical Templating of
Oligopeptides by Cyclodextrin Dimers," Bioorg. Med. Chem. 11, 2649-2653
(2003).
2002 Top
406.
S. Moore, J. A. Askew, G. L. Gibson, A. Aborgrein, T. Huckerby, O. M. A.
El-Agnaf, D. Allsop, D. K. Leung, and R. Breslow, "Novel cyclodextrin
dimers and trimers as inhibitors of amyloid peptide aggregation,"
Neurobiology of Aging 23, S105 (2002).
405.
L. Liu, M. Rozenman, and R. Breslow, "Hydrophobic Effects on Rates and
Substrate Selectivities in Polymeric Transaminase Mimics," J. Am. Chem.
Soc. 124, 12660-12661 (2002).
404.
L. Liu, M. Rozenman, and R. Breslow, "Stereoselectivity in Reactions of
Amino Acids Catalyzed by Pyridoxal Derivatives Carrying Rigidly-Attached
Chirally-Mounted Basic Groups-Transamination, Racemization, Decarboxylation,
Retro-Aldol Reaction, and Aldol Condensations," Bioorg. Med. Chem. 10,
3973-3979 (2002).
403. J. Yang, B. Gabriele, S. Belvedere, Y. Huang, and R.
Breslow, "Catalytic Oxidations of Steroid Substrates by Artificial
Cytochrome P-450 Enzymes," J. Org. Chem. 67, 5057-5067 (2002).
402. R. Breslow and Z. Fang, "Hydroxylation of Steroids
with an Artificial P-450 Catalyst Bearing Synthetic Cyclophanes as Binding
Groups," Tetrahedron Lett.
43, 5197-5200 (2002).
401.
R. Breslow, "Biomimetic Regioselective Template-Directed
Functionalizations: An Update," CHEMTRACTS Org. Chem., 15, 59-68 (2002).
400.
L. Liu and R. Breslow, "A Potent Polymer/Pyridoxamine Enzyme Mimic,"
J. Am. Chem. Soc. 124, 4978-4979 (2002).
399. R. Breslow, K. Groves, and M. Uljana Mayer,
"Antihydrophobic Cosolvent Effects for Alkylation Reactions in Water
Solution, Particularly Oxygen versus Carbon Alkylations of Phenoxide
Ions," J. Am. Chem. Soc. 124, 3622-3635 (2002).
398.
R. Breslow, J. Yan, and S. Belvedere, "Catalytic Hydoxylation of Steroids
by Cytochrome P-450 Mimics. Hydroxylation at C-9 with Novel
Catalysts and Steroid Substrates," Tetrahedron Lett. 43, 363-365 (2002).
397. R. Breslow, J. Yang, and J. Yan, "Biomimetic
Hydroxylation of Saturated Carbons with Artificial Cytochrome P-450
Enzymes-Liberating Chemistry from the Tyranny of Functional Groups,"
Tetrahedron 58, 653-659 (2002).
2001 Top
396.
P. A. Marks, V. M. Richon, R. Breslow, and R. A. Rifkind, "Histone
Deacetylase Inhibitors as New Cancer Drugs," Curr. Opin. Oncol. 13, 477-483 (2001).
395. M. Leivers and R. Breslow, "Concerning Two-Metal Cooperativity
in Model Phosphate Hydrolysis," Bioorg. Chem. 29, 345-356 (2001).
394.
S. D. P. Baugh, Z. Yang, D. K. Leung, D. M. Wilson, and R. Breslow, "
Cyclodextrin Dimers as Cleavable Carriers of Photodynamic Sensitizers," J.
Am. Chem. Soc. 123, 12488 -12494 (2001).
393.
P. A. Marks, R. A. Rifkind, V. M. Richon, R. Breslow, T. Miller and W. K.
Kelly, "Histone Deacetylases and Cancer: Causes and Therapies,"
Nature Reviews Cancer 1, 194-202 (2001).
392. R. Breslow, "Cyclodextrin Derivatives as Mimics of Enzymes
and Antibodies," Biolog.
J. Armenia 53, 117-120 (2001).
391.
S. Belvedere and R. Breslow , "Regioselective
Oxidation of Steroids by a Manganese Porphyrin Carrying Metal Coordinating
Groups," Bioorg. Chem. 29, 321-331 (2001).
390.
D. K. Leung, J. H. Atkins, and R. Breslow, "Synthesis and Binding
Properties of Cyclodextrin Trimers," Tetrahedron Lett. 42,
6255-6258 (2001).
389.
L. M. Butler, Y. Webb, D. B. Agus, B. Higgins, T. R. Tolentino, M. C. Kutko, M.
P. LaQuaglia, M. Drobnjak, C. Cordon-Cardo, H. I. Scher, R. Breslow, V. M.
Richon, R. A. Rifkind, and P. A. Marks, "Inhibition of Transformed Cell
Growth and Induction of Cellular Differentiation by Pyroxamide, an Inhibitor of
Histone Deacetylase," Clinical Cancer Research 2001, 7, 962-970 (2001).
388. L. Liu and R. Breslow, "Selective Racemization in
Preference to Transamination Catalyzed by Pyridoxal Enzyme Analogs,"
Tetrahedron Lett. 42,
2775-2777 (2001).
2000 Top
387.
R. Breslow, "Biomimetic Selectivity," The Chemical Record 2000, 1,
3-11 (2000).
386.
J. Yang and R. Breslow, "Regioselective Oxidations of Equilenin
Derivatives Catalyzed by a Rhodium (III) Porphyrin Complex&emdash;Contrast with the Manganese (III) Porphyrin,"
Tetrahedron Lett. 41, 8063-8067 (2000).
385.
R. Breslow, "Extending Nature,", Proc. Amer.
Phil. Soc. 144, 267-274 (2000).
384. R. Breslow, S. Belvedere, and L. Gershell,
"Development of Cytodifferentiating Agents for Cancer Chemotherapy,"
Helv. Chim. Acta,
83, 1685-1692 (2000).
383. N. Nesnas, J. Lou, and R. Breslow, "The Binding of
Cocaine to Cyclodextrins," Bioorg. & Med. Chem. Lett., 10, 1931-1933
(2000).
382. J. Yang and R. Breslow, "Selective Hydroxylation of a
Steroid at C-9 by an Artificial Cytochrome P-450," Angew. Chem. Int. Ed. 39, 2692-2694 (2000).
381. R. Breslow, S. Belvedere, L. Gershell, and D. Leung,
"The Chelate Effect in Binding, Catalysis, and Chemotherapy," Pure
Appl. Chem. 72, 333-342 (2000).
380.
D. K. Leung, Z. Yang, and R. Breslow, "Selective Disruption of Protein
Aggregation by Cyclodextrin Dimers," Proc. U.S. Natl. Acad. Sci. 97,
5050-5053 (2000).
379.
J.Yan and R. Breslow, "An Enzyme Mimic that Hydrolyzes an Unactivated
Ester with Catalytic Turnover," Tetrahedron Lett. 41,
2059-2062 (2000).
378.
J. Yang, R. Weinberg, and R. Breslow, "The Hydroxylation and Amidation of
Equilenin Acetate Catalyzed by Chloro[5,10,15,20-tetrakis(pentafluorophenyl)porphyrinato]manganese(III)"
Chem. Commun. 531-532 (2000).
1990 - 1999 Top
377. A. Ruebner, Z. Yang, D. Leung, and R. Breslow, "A
Cyclodextrin Dimer with a Photocleavable Linker as a Possible Carrier for the
Photosensitizer in Photodynamic Tumor Therapy," Proc. U.S. Natl. Acad.
Sci. 96, 14692-14693 (1999).
376.
R. Breslow, "Biomimetic Reactions Directed by Templates and Removable
Tethers," in Templated Organic Synthesis, F. Diederich and P. Stang, eds,
Wiley-VCH, Weinheim, Germany, 1999, chap. 6.
375.
M. S. Finnin, J. R. Donigian, A. Cohen, V. M. Richon, R. A. Rifkind, P. A.
Marks, R. Breslow, and N. A. Pavletich, "Structures of a Histone
Deacetylase Homologue Bound to the TSA and SAHA Inhibitors," Nature 401,
188-193 (1999).
374. R. Breslow, K. Groves, and M. U. Mayer,
"Antihydrophobic Cosolvent Effects in Organic Displacement
Reactions," Org. Lett.
1, 117-120 (1999).
373. E. Fasella, S. D. Dong, and R. Breslow, "Reversal of
Optical Induction in Transamination by Regioisomeric Bifunctionalized
Cyclodextrins," Bioorg.
Med. Chem. 7, 709-714 (1999).
372.
R. Breslow, "Antiaromatic Triplet Ground State Nolecules: Building Blocks
for Organic Magnets," in Magnetic Properties of Organic Materials, P. M.
Lahti, ed., Marcel Dekker, New York, 1999, chap. 3.
371.
Y. Webb, X. Zhou, L. Ngo, V. Cornish, J. Stahl, H. Erdjument-Bromage, P.
Tempst, R. A. Rifkind, P. A. Marks, R. Breslow, and V. M. Richon,
"Photoaffinity Labeling and Mass Spectrometry Identify Ribosomal Protein
S3 as a Potential Target for Hybrid Polar Cytodifferentiation Agents." J. Biol.
Chem., 274, 14280-14287 (1999).
370.
R. Breslow and N. Nesnas, "Burst Kinetics and Turnover in an Esterase
Mimic," Tetrahedron Lett. 40, 3335-3338 (1999).
369.
P. A. Marks, V. M. Richon, R. Breslow, and R. A. Rifkind, "Hybrid polar
inducers of transformed cell differentiation/apoptosis. From
the cell to the clinic," C. R. Acad. Sci. Paris/Life Sciences, 322,
161-165 (1999).
368.
M. Sprecher, R. Breslow, R. Philosof-Oppenheimer, and E. Chavet, "Steroid
Phosphate Esters," Tetrahedron , 55, 5465-5482
(1999).
367.R. Breslow, F. McCormick, and C. Werner, "A Stable
Cyclopentenyl Trication Derivative," Tetrahedron Lett. 40, 2447-2448 (1999).
366. Y. Webb, L. Ngo, V. M. Richon, R. Breslow, R. Rifkind, and
P. A. Marks, "Identification of a Poetential Target for Hybrid Polar
Cytodifferentiation Agents," Proc. Amer. Assoc. for Cancer Res. 39, 108
(1998).
365. R. Breslow, K. Groves, and M. U. Mayer, "The
Hydrophobic Effect as a Mechanistic Tool," Pure & Appl. Chem. 70,
1933-1938 (1998).
364.
S. D. Dong and R. Breslow, "Bifunctional Cyclodextrin Metalloenzyme
Mimics," Tetrahedron Lett. 39, 9343-9346 (1998).
363.
D.-Q. Yuan, S. D. Dong, and R. Breslow,
"Cyclodextrin-based Class I Aldolase Enzyme Mimics to Catalyze Crossed
Aldol Condensations," Tetrahedron Lett. 39, 7673-7676
(1998).
362.
M. Uljana Mayer and R. Breslow, "Antihydrophobic Evidence for the Single
Electron Transfer Mechanism of Nucleophilic Substitution," J. Am. Chem.
Soc,. 120, 9098-9099 (1998).
361.
R. Breslow, "Water as a Solvent for Chemical Reactions," in
"Green Chemistry," P. T. Anastas and T. C. Williamson, eds, Oxford
Press, New York, 1998, chap. 13.
360.
R. Breslow and S. D. Dong, "Biomimetic Reactions Catalyzed by
Cyclodextrins and Their Derivatives," Chem. Rev. 98, 1997-2011 (1998).
359. R. Breslow, "Studies in Biomimetic Chemistry,"
Pure & Appl. Chem. 70, 267-270 (1998).
358.
R. Breslow, Bioorganic Chemistry: A Natural and Unnatural Science, J. Chem. Ed.
75, 705-718 (1998).
357. R. Breslow, B. Gabriele, and J. Yang, "Geometrically
Directed Selective Steroid Hydroxylation with High Turnover by a Fluorinated
Artificial Cytochrome P-450," Tetrahedron Lett. 39, 2887-2890 (1998).
356.
R. Breslow, Z. Yang, R. Ching, G. Trojandt, and F. Odobel, "Sequence
Selective Binding of Peptides by Artificial Receptors in Aqueous
Solution," J. Am. Chem. Soc. 120, 3536-3537 (1998).
355.
V. M. Richon, S. Emiliani, E. Verdin, Y. Webb, R. Breslow, R. A. Rifkind, and
P. A. Marks, "A Class of Hybrid Polar Inducers of Transformed Cell
Differentiation Inhibits Histone Deacetylases," Proc. Natl. Acad. Sci. USA
95, 3003-3007 (1998).
354.
R. Breslow, "Biomimetic Chemistry: a Frontier at the Chemistry/Biology
Interface," Chem. & Biol. 5, R27-28 (1998).
353. R. Breslow, Y. Huang, and J. Yang, "An Artificial
Cyctochrome P450 that Hydroxylates Unactivated Carbons with Regio- and
Stereoselectivity and Useful Catalytic Turnovers," Proc. Natl. Acad. Sci.
USA 94, 11156-11158 (1997).
352. Z. Yang and R. Breslow, "Very Strong Binding of
Lithocholic Acid to ß-Cyclodextrin," Tetrahedron Lett. 38, 6171-6172 (1997).
351. M. Rezac and R. Breslow, "A Mutase Mimic with
Cobalamin Linked to Cyclodextrin," Tetrahedron Lett. 38, 5763-5766 (1997).
350. R. Breslow,"Imitating Antibodies and Enzymes,"
Proc. Robert A Welch Foundation 40th Conference on Chem. Res. 40, 1-11 (1997).
349.
R. Breslow, X. Zhang, and Y. Huang, "Selective Catalytic Hydroxylation of
a Steroid by an Artificial Cytochrome P-450 Enzyme," J. Am. Chem. Soc,. 119, 4535-4536 (1997).
348.
R. Breslow, "What will Physical Organic Chemistry Achieve in the 21st
Century," Pure & Appl. Chem. 69, 223-225 (1997).
347.
J. Klicic, Y. Rubin, and R. Breslow, "Approaches to Stable Cyclopropenyl
Anions: tris-1,2,3-p-Nitrophenylcyclopropene,"
Tetrahedron, 53, 4129-4136 (1997).
346.
R. Xu and R. Breslow, "Triphenylcyclopropenium Bromide," Org. Syn.,
74, 72-75 (1997).
345. B. Zhang and R. Breslow, "Ester Hydrolysis by a
Catalytic Cyclodextrin Dimer Enzyme Mimic with a Metallobipyridyl Linking
Group," J. Am. Chem. Soc., 119, 1676-1681 (1997).
344. R. Breslow, "Bifunctional Binding and Catalysis,"
NATO ASI Ser., Ser. E, 320, 113-135 (1996).
343.
R. Breslow, X. Zhang, R. Xu, M. Maletic, and R. Merger, "Selective
Catalytic Oxidation of Substrates that Bind to Metalloporphyrin Enzyme Mimics
Carrying Two of Four Cyclodextrin Groups and Related Metallosalens," J.
Am. Chem. Soc, 118, 11678-11679 (1996).
342. R. Breslow and C. Schmuck, "The Mechanism of
Thiazolium Catalysis," Tetrahedron Lett. 37, 8241-8242 (1996).
341.R.
Breslow and T. L. Sheppard, "Why Natural DNA is Based on 2'-Deoxyribose,
with 3',5' Phosphodiester Links," Pure &
Appl. Chem. 68, 2037-2041 (1996).
340.
T. L. Sheppard and R. C. Breslow, "Selective Binding of RNA, but Not DNA,
by Complementary 2',5'-Linked DNA," J. Am. Chem.
Soc., 40, 9810-9811 (1996).
339.
R. Breslow and W. H. Chapman, Jr., "On the Mechanism of Action of
Ribonuclease A: Relevance of Enzymatic Studies with a p-Nitrophenylphosphate Ester and a Thiophosphate Ester," Proc.
Natl. Acd. Sci. USA, 93, 10018-10021 (1996).
338.
R. Breslow and B. Zhang, "Cholesterol Recognition and Binding by
Cyclodextrin Dimers," J. Am. Chem. Soc., 118, 8495-8496 (1996).
337. R. Breslow, R. Connors, and Z. Zhu, "Mechanistic
Studies Using Antihydrophobic Agents," Pure & Appl. Chem., 68,
1527-1533 (1996).
336. M. Maletic, H. Wennemers, D. Q. McDonald, R. Breslow, and
W. C. Still,
"Selective Binding of Dipeptides L-Phe-D-Pro and D-Phe-L-Pro to
ß-Cyclodextrin," Angew. Chem. Int. Ed. Engl.,
35, 1490-1492 (1996)
335.
R. Breslow and C. Schmuck, "Goodness of Fit in Complexes between
Substrates and Ribonuclease Mimics: Effects on Binding, Catalytic Rate
Constants, and Regiochemistry," J. Am. Chem. Soc. 118, 6601-6605 (1996).
334.
R. Breslow, S. D. Dong, Y. Webb, and R. Xu, "Further Studies on the
Buffer-Catalyzed Cleavage and Isomerization of Uridyluridine. Medium and Ionic
Strength Effects on Catalysis by Morpholine, Imidazole, and Acetate Buffers
Help Clarify the Mechanisms Involved and Their Relationship to the Mechanism
Used by the Enzyme Ribonuclease and by a Ribonuclease Mimic," J. Am. Chem.
Soc. 118, 6588-6600 (1996).
333. V. M. Richon, Y. Webb, R. Merger, T. Sheppard, B. Jursic,
L. Ngo, F. Civoli, R. Breslow, R. A. Rifkind, and P. A. Marks, " Second
Generation Hybrid Polar Compounds are Potent Inducers of Transformed Cell
Differentiation," Proc. Natl. Acd. Sci. USA, 93, 5705-
5708 (1996).
332.
R. Breslow and R. Connors, "Antihydrophobic Cosolvent Effects Detect Two
Different Geometries for an SN2 Displacement and the Change to a
Single-Electron Transfer Mechanisms in Related Cases," J. Am. Chem. Soc.
118, 6323-6324 (1996).
331. R. Breslow, J. Desper, and Y. Huang, "A Selective
Intramolecular Aldol Condensation Directed by a Bifunctional Enzyme
Mimic," Tetrahedron Lett.
37, 2541-2544 (1996).
330.
J. Light and R. Breslow, "A Water-soluble Tin Hydride: Tris[3-(2-
methoxyethoxy)propyl]stannane", Org. Synth. 72,199
(1995).
329. R. Breslow, "Binding and Catalysis with Flexible Locks
and Flexible Keys", Supramolecular Chemistry, 66, 41-47 (1995).
328.
R. Breslow and Z. Zhu, "Quantitative Antihydrophobic Effects as Probes for
Transition State Structures. 2. Diels-Alder Reactions", J. Am. Chem. Soc.
117, 9923-9924 (1995).
327.
R. Breslow and R. V. Connors, "Quantitative Antihydrophobic Effects as
Probes for Transition State Structures. 1. Benzoin
Condensation and Displacement Reactions", J. Am. Chem. Soc. 117, 6601-6602
(1995).
326.
W. H. Chapman, Jr., and R. Breslow, "Selective Hydrolysis of Phosphate
Esters, Nitrophenyl Phosphates and UpU, by Dimeric Zinc Complexes Depends on
the Spacer Length", J. Am. Chem. Soc. 117, 5462-5469 (1995).
325.
R. Breslow, "Studies on Bioorganic Reactions and Mechanisms", in
Organic Reactivity: Physical and Biological Aspects, B. T. Golding, R. J.
Griffin, and H. Maskill, eds., The Royal Society of
Chemistry, Cambridge England, 1995, Special Publication No. 148, pp. 3-24.
324. R. Breslow, P. J. Duggan, D. Wiedenfeld, and S. T. Waddell,
"The Binding Properties of Cyclophane Dimers", Tetrahedron Lett. 36, 2707- 2710 (1995).
323. R. Breslow, "Biomimetic Chemistry and Artificial
Enzymes: Catalysis by Design", Accts. Chem. Res. 28, 146-153 (1995).
322. R. Breslow, S. Halfon, and B. Zhang, "Molecular
Recognition by Cyclodextrin Dimers", Tetrahedron, 51, 377-388 (1995).
321. M. Sprecher, R. Breslow, O. Uziel, and T. M. Link,
"Monosubstituted 2,2'-Bipyridines", OPPI Briefs 26, 696-701 (1994).
320.
J. M. Desper and R. Breslow, "Catalysis of an Intramolecular Aldol
Condensation by Imidazole-Bearing Cyclodextrins", J. Am. Chem. Soc. 116,
12081-12082 (1994).
319.
J. T. Koh, L. Delaude, and R. Breslow, "Geometric Control of a
Pyridoxal-Catalyzed Aldol Condensation", J. Am. Chem. Soc. 116,
11234-11240 (1994).
318.
L. P. Le, A. Keren, G. M. Luke, W. D. Wu, Y. J Uemura, W. S. Jenks, A. Graff,
R. Breslow, P. Dosanjh "mSR Studies in an I2-Doped Phenylenediamine
Polymer", Hyperfine Interactions 85 287-292 (1994).
317. T. L. Sheppard, A. T. Rosenblatt, and R. Breslow,
"Preparation of 2'-O- (b-Cyanoethyl phosphoramidites) of 3'-Deoxycytidine
and 3'- Deoxyguanosine and their Use for Solid-Phase Synthesis of
Oligodeoxynucleotides Containing 2',5'-Phosphodiester
Linkages", J. Org. Chem. 59, 7243-7248 (1994).
316. R. Breslow, "The Chelate Effect in Binding, Catalysis,
and Chemotherapy", Recl.
Trav. Chim. Pays-Bas 113, 493 (1994).
315.
R. Breslow, "Hydrophobic and Antihydrophobic Effects on Organic Reactions
in Aqueous Solution", in Structure and Reactivity in Aqueous Solution, C.
J. Cramer and D. G. Truhlar, eds., American Chemical
Society, Washington, D.C., 1994, pp. 291-302.
314.
R. Breslow and B. Zhang, "Cleavage of Phosphate Esters by a Cyclodextrin
Dimer Catalyst that Binds the Substrates Together with La3+ and Hydrogen
Peroxide", J. Am. Chem. Soc. 116, 7893-7894 (1994).
313.
R. Breslow, "Bifunctional Acid-Base Catalysis by Imidazole Groups in
Enzyme Mimics", J. Mol. Cat. 91, 161-174 (1994).
312.
R. Breslow, "Biomimetic Chemistry", Pure & Appl. Chem. 66, 1573-
1582 (1994).
311. R. Breslow and R. Kim, "The Thiazolium Catalyzed
Benzoin Condensation with Mild Base Does not Involve a "Dimer"
Intermediate", Tetrahedron Lett.
35, 699-702 (1994).
310. R. Breslow, "The Correct Use of Partitioning Ratios in
the Derivation of Rate Equations" J. Chem. Ed. 71, 999-1000 (1993).
309.
R. Breslow and A. Graff, "Geometry of Enolization Using a Bifunctional
Cyclodextrin-Based Catalyst" J. Am. Chem. Soc. 115, 10988-10989 (1993).
308.
R. Breslow and R. Xu, "Quantitative Evidence for the Mechanism of RNA
Cleavage by Enzyme Mimics. Cleavage and Isomerization of UpU
by Morpholine Buffers" J. Am. Chem. Soc. 115, 10705-10713(1993).
307.
R. Jin, W. H. Chapman, Jr., A. R. Srinivasan, W. K. Olson, R. Breslow, and K.
J. Breslauer, "Comparative Spectroscopic, Calorimetric, and Computational
Studies of Nucleic Acid Complexes with 2',5"-
versus 3',5"-phosphodiester Linkages," Proc. Natl. Acad. Sci. USA 90,
10568- 10572 (1993).
306. B. Zhang and R. Breslow, "Enthalpic Domination of the
Chelate Effect in Cyclodextrin Dimers" J. Am. Chem. Soc. 115, 9353-9354
(1993).
305.
R. Breslow, "Model Studies Clarify an Enzyme Mechanism" Citation
Classic, Curr. Cont. Physical, Chemical and Earth Sciences 33, 8 (1993). Curr.
Cont. Engineering, Techanology, and Applied Sciences 24, 8 (1993).
304. R. Breslow, "Bifunctional Binding and Catalysis",
Supramol. Chem.
1, 111-118 (1993).
303. R. Breslow and D. Wiedenfeld, "Quinoline and Acridine
Templates in Selective Steroid Chlorinations", Tetrahedron Lett. 34, 1107-1110 (1993).
302. R. Breslow, "Kinetics and Mechanism in RNA
Cleavage", Proc. Natl. Acad. Sci. USA 90, 1208-1211 (1993).
301. R. Breslow and R. Xu, "Recognition and Catalysis in
Nucleic Acid Chemistry", Proc. Natl. Acad. Sci. USA 90, 1201-1207(1993).
300.
R. Breslow, "Molecular Recognition", Proc. Natl. Acad. Sci. USA 90,
1139 (1993).
299. R. Breslow, "Selective Binding and Catalysis by
Cyclodextrins", Minutes of the Sixth International Symposium on
Cyclodextrins, Editions de Sante, Paris, 625-630 (1992).
298.
R. Breslow, "Bifunctional Binding and Catalysis in Host-Guest
Chemistry", Israel Jour. Chem. 32 , 23-30 (1992).
297.
P. A. Marks, R. A. Rifkind, V. Richon, T. Powell, X. Busquets, L. Leng, H.
Kiyokawa, J. Michaeli, B. Jursic, and R. Breslow, "Hexamethylene
Bisacetamide and Related Agents as Inducers of Differentiation of Transformed
Cells: Mechanism of Action and Potential for Cancer Therapy", Concise
Reviews in Experimental and Clinical Hematology, Martin J. Murphy, Ed.,
AlphaMed Press, Dayton, Ohio, (1992) 91-99.
296. R. Breslow and S. Halfon, "Quantitative Effects of
Antihydrophobic Agents on Binding Constants and Solubilities in Water",
Proc. Natl. Acad. Sci. USA 89, 6916-6918 (1992).
295.
J. P. Dougherty, C. J. Rizzo, and R. Breslow, "Oligonucleotides That
Contain 2',5" Linkages: Synthesis and
Hybridization Properties", J. Am. Chem. Soc. 114, 6254-6255 (1992).
294.
R. Breslow and T. Link, "Chemical Degradation of Steroid Side Chains. Efficient Conversion of Cholestanol to Corticosteroid
Intermediates", Tetrahedron Lett. 33, 4145-4148
(1992).
293.
C. J. Rizzo, J. P. Dougherty and R. Breslow, "3'-Deoxy-2'-
Phosphoramidates of Adenosine and 5-Methyluridine Used for the Solid Phase
Synthesis of Unnatural 3'-Deoxy-2',5"-Oligonucleotides",
Tetrahedron Lett. 33, 4129-4132 (1992).
292. R. Breslow and B. Zhang, "Very Fast Ester Hydrolysis
by a Cyclodextrin Dimer with a Catalytic Linking Group", J. Am. Chem. Soc.
114, 5882-5883 (1992).
291. R. Breslow, "Binding and Catalysis in Water",
Supramolecular Chemistry, 411-428 (1992).
290.
R. Breslow, P. J. Duggan, and J. P. Light ,
"Cyclodextrin-B12, a Potential Enzyme-Coenzyme Mimic", J. Am. Chem.
Soc. 114, 3982-3983 (1992).
289.
G. A. Crispino and R. Breslow, "Synthesis of Tripyridiniumpropenyl Anions
from Tripyridiniumcyclopropanes and -cyclopropenes" J. Org. Chem. 57,
1849-1855 (1992).
288. R. Breslow, "Oxidation by Remote Functionalization
Methods", in "Comprehensive Organic Synthesis", Barry M. Trost,
ed., vol. 7, 39-53, Pergamon Press, Oxford (1991).
287.
R. Breslow, "How do Imidazole Groups Catalyze the Cleavage of RNA in
Enzyme Models and in Enzymes? Evidence from "Negative
Catalysis"", Accts. Chem. Res. 24, 317-324 (1991).
286.
D. Wiedenfeld and R. Breslow, "Directed Formation of Carbon- Bromine and
Carbon-Sulfur Bonds by Tandem Radical Chain Reactions", J. Am. Chem. Soc.
113, 8977-8978 (1991).
285.
R. Breslow, B. Jursic, Z. F. Yan, E. Friedman, L. Leng, L. Ngo, R. A. Rifkind,
and P. A. Marks, "Potent Cytodifferentiating Agents Related to
Hexamethylenebisacetamide", Proc. Natl. Acad. Sci. USA 88, 5542-5546
(1991).
284. R. Breslow, "Hydrophobic Effects on Simple Organic
Reactions in Water", Accts.
Chem. Res. 24, 159-164 (1991).
283.
R. Breslow and D.-L. Huang, "Effects of Metal
Ions, including Mg2+ and Lanthanides, on the Cleavage of Ribonucleotides and
RNA Model Compounds", Proc. Natl. Acad. Sci. USA 88, 4080-4083 (1991).
282.
R. Breslow and Carmelo J. Rizzo, "Chaotropic Salt Effects in a
Hydrophobically Accelerated Diels-Alder Reaction", J. Am. Chem. Soc. 113,
4340-4341 (1991).
281. R. Breslow and J. W. Canary, "Rapid Nucleophilic
Substitutions on Cyclopentadienyl Iodide and Bromide", J. Am. Chem. Soc.
113, 3950- 3952 (1991).
280.
R. Breslow, "Enzyme Mimics", Ciba Foundation Symposium 158, 115-127
(1991).
279.
R. Breslow, E. Anslyn, and D.-L. Huang,
"Ribonuclease Mimics", Tetrahedron 47, 2365-2376 (1991).
278. R. Breslow and G. A. Crispino, "Tripyridylcyclopropene
Derivatives and their Conversion to Hexapyridylbenzene", Tetrahedron Lett. 32, 601-604 (1991).
277.
R. Breslow and S. Chung, "Strong Binding of Ditopic Substrates by a Doubly
Linked Occlusive C1 "Clamshell" as Distinguished from an Aversive C2
"Loveseat" Cyclodextrin Dimer", J. Am. Chem. Soc. 112, 9659-9660
(1990).
276.
P. A. Marks, R. A. Rifkind and R. Breslow, "Induced Differentiation of
Transformed Cells: Mechanism of Action and Application in Cancer Therapy"
in Molecular Basis of Haematopoiesis , L. Sachs, N. G.
Abraham, C. Weidemann, A. S. Levine and G. Konwalinka, eds., Intercept, Ltd.,
Andlover, Great Britain, 579-586 (1990).
275.
R. Breslow and D.-L. Huang, "A Negative Catalytic
Term Requires a Common Intermediate in the Imidazole Buffer Catalyzed Cleavage
and Rearrangement of Ribodinucleotides", J. Am. Chem. Soc. 112, 9621-9623
(1990).
274.
P. White and R. Breslow, "Molecular Mechanics Calculations on
Template-Directed Steroid Chlorinations: Are Transition States Rigidified by
the Geometric Trajectory Requirements for Effective Energy Transfer?" J.
Am. Chem. Soc. 112, 6842-6847 (1990).
273.
R. Breslow, "Enzyme Mimics", Pure & Appl. Chem., 62, 1859-1866
(1990).
272.
R. Breslow, J. W. Canary, M. Varney, S. T. Waddell, and D. Yang,
"Artificial Transaminases Linking Pyridoxamine to Binding Cavities:
Controlling the Geometry", J. Am. Chem. Soc. 112, 5212-5219 (1990).
271. J. Light and R. Breslow, "A Water Soluble Tin Hydride
Reagent" Tetrahedron Lett.
31, 2957-2958 (1990).
270.
R. Breslow, D. Berger, and D.-L. Huang,
"Bifunctional Zinc-Imidazole and Zinc-Thiophenol Catalysts" J. Am.
Chem. Soc. 112, 3686-3687 (1990).
269.
R. Breslow, "Partitioning Ratios and a Biochemical Kinetic Dilemma"
J. Chem. Ed. 67, 228-229 (1990).
268. R. Breslow, "Enzyme Mimics" UCLA Symposia on Mol.
and Cell. Biol.
110, 135-144 (1990).
267.
J. Light and R. Breslow, "The Hydrolysis of a Co(III)
Chelated Amide Catalyzed by an Internal Phosphonic Acid Group" Bioorg. Chem. 18, 63-77 (1990).
266. R. Breslow and S. Chung, "Additional Flexibility
Solves the Leaving Group Problem in Cyclodextrin Acylation" Tetrahedron
Lett. 31,
631-634 (1990).
265.
R. Breslow and T. Guo, "Surface Tension Measurements Show that Chaotropic
Salting-in Denaturants are not just Water-structure Breakers" Proc. Natl.
Acad. Sci. USA 87, 167-169 (1990).
1980-89 Top
264.
P. A. Marks, R. Breslow, and R. A. Rifkind, "Induced Cytodifferentiation
of Transformed Cells: an Approach to Cancer Treatment" Anticancer Drugs,
H. Tapiero, J. Robert, and T. J. Lampidis, eds., John
Libbey Eurotext Ltd. (1989).
263.
P. A. Marks, R. Breslow, and R. A. Rifkind, "Induced Cytodifferentiation
of Transformed Cells: an Approach to Cancer Treatment" J. Cellular
Pharmacol. 7-11 (1989).
262. R. Breslow, "4n Pi Electron Triplet Species and their
Potential Use in Organic Ferromagnets" Mol. Cryst. Liq. Cryst. 176, 199-210 (1989).
261. E. Anslyn and R. Breslow, "Proton Inventory of a
Bifunctional Ribonuclease Model" J. Am. Chem. Soc. 111, 8931-8932 (1989).
260. R. Breslow, N. Greenspoon, T. Guo and R. Zarzycki, "Very
Strong Binding of Appropriate Substrates by Cyclodextrin Dimers" J. Am.
Chem. Soc. 111, 8296-8297 (1989).
259. R. Breslow and S. Chung, "A Novel Synthesis of
Substituted Imidazoles, and a Reexamination of a Purported Chymotrypsin
Model" Tetrahedron Lett.
30, 4345-4346 (1989).
258.
P. A. Marks, R. Breslow, R. A. Rifkind, L. Ngo, and R. Singh,
"Polar/apolar Chemical Inducers of Differentiation of Transformed Cells:
Strategies to Improve Therapeutic Potential" Proc. Natl. Acad. Sci. USA,
86, 6358-6362 (1989).
257. E. Anslyn and R. Breslow, "Geometric Evidence on the
Ribonuclease Model Mechanism", J. Am. Chem. Soc. 111, 5972-5973 (1989).
256. R. Breslow, A. B. Brown, R. D. McCullough and P. W. White,
"Substrate Selectivity in Epoxidation by Metalloporphyrin and Metallosalen
Catalysts Carrying Binding Groups", J. Am. Chem. Soc. 111, 4517-4518
(1989).
255.
E. Anslyn and R. Breslow, "On the Mechanism of Catalysis by Ribonuclease:
Cleavage and Isomerization of the Dinucleotide UpU by Imidazole Buffers",
J. Am. Chem. Soc. 111, 4473-4482 (1989).
254.
R. Breslow, Deeng-Lih Huang, and E. Anslyn,"On the Mechanism of Action of
Ribonucleases: Dinucleotide Cleavage Catalyzed by Imidazole and Zn2+",
Proc. Natl. Acad. Sci. USA 86, 1746-1750 (1989).
253. R. Batra and R. Breslow, "The Radical Relay
Chlorination of Flexible Nicotinate Esters", Heterocycles 28, 23-28
(1989).
252.
R. Batra and R. Breslow, "Double Functionalization of Cholestanol Directed
by Selective Bifunctional Templates", Tetrahedron Lett.,
30, 535-538 (1989).
251.
H.-J. Thiem, M. Brandl and R. Breslow, "Molecular
Modelling Calculations on the Acylation of b-Cyclodextrin by Ferroceneacrylate
Esters", J. Am. Chem. Soc. 110, 8612-8616 (1988).
250.
R. Breslow and S. Singh, "Phosphate Ester Cleavage Catalyzed by
Bifunctional Zinc Complexes: Comments on the 'p-Nitrophenyl Ester
Syndrome'", Bioorg. Chem. 16, 408-417 (1988).
249.
R. Breslow, "Biomimetic Regioselective Template-directed
Functionalizations", Chemtracts Org. Chem. 1, 333-348 (1988).
248.
R. Breslow, J. Chmielewski, D. Foley, B. Johnson, N. Kumabe, M. Varney, and R.
Mehra, "Optically Active Amino Acid Synthesis by Artificial Transaminase
Enzymes", Tetrahedron, 44, 5515-5524 (1988).
247.
R. Breslow, "Artificial Enzymes: Studies Relevant to Reaction Mechanisms
of Enzymes and Enzymes Models", Proc. Robert A. Welch Found. Conf. on Chem. Res., 31 73-89 (1988).
246.
R. Breslow and T. Guo, "Diels-Alder Reactions in Nonaqueous Polar
Solvents. Kinetic Effects of Chaotropic and Antichaotropic
Agents and of b-Cyclodextrin", J. Am. Chem. Soc., 110, 5613 (1988).
245. R. Breslow, "Molecules that Mimic Enzymes", New
Scientist, 119, 44 (1988).
244. J. Thomaides, P. Maslak, and R. Breslow,
"Electron-Rich Hexasubstituted Benzene Derivatives and their Oxidized Cation
Radicals, Dications with Potential Triplet Ground States, and
Polycations", J. Am. Chem. Soc., 110, 3970 (1988).
243.
R. Breslow and E. Kool, "A g-Cyclodextrin Thiazolium Salt Holoenzyme Mimic
for the Benzoin Condensation", Tetrahedron Lett.,
29, 1635 (1988).
242.
E. T. Kool and R. Breslow, "Dichotomous Salt Effects in the Hydrophobic
Acceleration of the Benzoin Condensation", J. Am. Chem. Soc., 110, 1596
(1988).
241. R. Breslow, "Selective Reactions Catalyzed by Enzyme
Mimics", Chemica Scripta, 27, 555 (1987).
240.
R. Breslow, "Artificial Enzymes", Cold Spring Harbor Symposia on
Quantitative Biology, 52, 75-81 (1987).
239.
R. Breslow, A. Adams, M. Brandl, T. Guo, and J. Hunger, "Heterocycles as
Templates in Directed Functionalization Reaction", Lectures in
Heterocyclic Chem., Vol. IX, 43 (1987).
238.
R. Breslow, M. Brandl, J. Hunger, N.J. Turro, K. Cassidy, K Krogh-Jespersen,
and J. D. Westbrook, "Pyridine Complexes of Chlorine Atoms", J. Am
Chem. Soc., 109, 7204-7026 (1987).
237.
T. J. Lepage and R. Breslow, "Charge-Transfer Complexes as Potential
Organic Ferromagnets", J. Am. Chem. Soc., 109, 6412-6421 (1987).
236. R. Breslow and T. Guo, "The Thioxanthone System as a
Template in Free Radical Relay Chlorination of a Steroid", Tet. Letters, 28, 3187-3188 (1987).